The technology used at Neuronano AB for Deep Brain Stimulation (DBS) is an electrode-cluster technology using a biodegradable carrier for implantation of the probe. The probe carrier, made from gelatin or other gel materials, provides a strong and robust vehicle for advancing the extremely thin electrodes to the target position, which in Neuronano’s case resides in deep structures of the brain.
- “The gelatin carrier almost acts like a “stealth vehicle” for the probe, making it possible to implant the electrodes with minimal impact on the neuronal tissue,” says Jens Schouenborg, Principal Inventor of Neuronano AB
After reaching the target the carrier probe dissolves, leaving the ultra-flexible electrodes covering the target area.
The biodegradable gelatin carrier probe is molded with very high precision in order to transport the thin electrodes to the exact target area. However, the carrier probe does not only act as an effective vehicle but also ensures very mild implantation, important to minimize surgical damage. This is achieved by creating a very slippery outer surface of the carrier probe during implantation, providing very low friction which in turn spares the brain tissue.
- My biggest motivation is to think about how our work will dramatically increase patients’ quality of life, says Robin Solnevik who works with fine mechanics and precision manufacturing at Neuronano.